Assistant professor

emilia.grzeda@up.poznan.pl

tel. +48 61 848 7651
nr pokoju 224

ORCID ID: 0000-0002-8798-991X
Research Gate

 

Scientific interests

Cognitive impairment in metabolic diseases, especially in diabetes.

Central regulation of the circulatory system functions (participation of cannabinergic receptors located in the paraventricular nucleus of the hypothalamus (PVN).

Effects of cafeteria diet on cognitive processes, inflammation, metabolic and hormonal status (sex differences, and the influence of the mother’s diet on the offspring).

CV

2012-2015 Research Assistant, Medical University of Białystok, Faculty of Pharmacy, Department of Experimental Physiology and Pathophysiology

2013 Institute of Molecular Psychiatry, University of Bonn

Institute of Pharmacology and Toxicology, University of Bonn

2012 May Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland

2007-2012 Research Assistant, Medical University of Białystok, Poland, Faculty of Medicine with the Division of Dentistry, Department of Pharmacology

2007 PhD in Medical Sciences, Medical University of Białystok, Poland, Faculty of Medicine with the Division of Dentistry, Department of Pharmacology, Supervisor – prof. dr hab. Róża Julia Wiśniewska

2001 Master in Environmental Biology, University of Białystok, Faculty of Biology and Chemistry. Supervisor – prof. dr hab. Marek Konarzewski

Projects

2012-2016 Participation in the research grant -Role of endocannabinoids in the regulation of the cardiovascular system, oxidative stress and heart metabolism in the models of primary and secondary hypertension (OPUS, 2012 – 2016; Principal investigator: Prof. Barbara Malinowska, Department of Experimental Physiology and Pathophysiology, Medical University of Białystok)

Publications

Grzęda E., Schlicker E., Toczek M., Zalewska I., Baranowska-Kuczko M., Malinowska B.: CB1 receptor activation in the rat paraventricular nucleus induces bi-directional cardiovascular effects via modification of glutamatergic and GABAergic neurotransmission. Naunyn-Schmiedeberg’s Archives of Pharmacology 2017; 390, 1: 25-35.

Toczek M., Baranowska-Kuczko M., Grzęda E., Pędzińska-Betiuk A., Weresa J., Malinowska B.: Age-specific influences of chronic administration of the fatty acid amide hydrolase inhibitor URB597 on cardiovascular parameters and organ hypertrophy in DOCA-salt hypertensive rats: Pharmacological Reports 2016; 68, 2: 363-369.

Grzęda E., Schlicker E., Łuczaj W., Harasim E., Baranowska-Kuczko M., Malinowska B.: Bi-directional CB1 receptor-mediated cardiovascular effects of cannabinoids in anaesthetized rats: role of the paraventricular nucleus. Journal of Physiology and Pharmacology 2015; 66, 3: 343-35.

Toczek M., Schlicker E., Grzęda E., Malinowska B.: Enhanced function of inhibitory presynaptic cannabinoid CB1 receptors on sympathetic nerves of DOCA-salt hypertensive rats. Life Sciences 2015: 138: 78-85.

Baranowska-Kuczko M., Kozłowska H., Kozłowski M., Schlicker E., Kloza M., Surażyński A., Grzęda E., Malinowska B.: Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. Naunyn-Schmiedeberg’s Archives of Pharmacology 2014; 387, 5: 477-486

Karabowicz P., Grzęda E., Baranowska-Kuczko M., Malinowska B.: Znaczenie endokannabinoidu 2-arachidonyloglicerolu w fizjologii i patofizjologii układu krążenia. Postępy Higieny i Medycyny Doświadczalnej 2014; 68: 814-827

Malinowska B., Grzeda E., Schlicker E.: Triphasic cardiovascular response to cannabinoids – Focus on underlying mechanisms. Pharmacol Rep 2014; 66 (2):332-333

Kozłowska H., Baranowska-Kuczko M., Schlicker E., Kozłowski M., Zakrzeska A., Grzęda E., Malinowska B.: EP3 receptor-mediated contraction of human pulmonary arteries and inhibition of neurogenic tachycardia in pithed rats. Pharmacological Reports 2012; 64, 6: 1526-1536.

Grzęda E., Wiśniewska R.J.: Effect of the class I metabotropic glutamate receptor antagonist AIDA on certain behaviours in rats with experimental chronic hyperammonemia. Advances in Medical Sciences 2009; 54,2:269-276.

Grzęda E., Wiśniewska R.J.: Differentiations of the effect of NMDA on the spatial learning of rats with 4 and 12 week diabetes mellitus. Acta Neurobiologiae Experimentalis 2008; 68: 398-406.

Grzęda E., Wiśniewska R. J., Wiśniewski K.: Effect of an NMDA receptor agonist on T-maze and passive avoidance test in 12-week streptozotocin-induced diabetic rats. Pharmacological Reports 2007; 59,6: 656-663.

Wiśniewski K., Fedosiewicz-Wasiluk M., Hoły Z.Z., Car H., Grzęda E.: Influence of NMDA, a potent agonist of glutamate receptors, on behavioral activity in 4-week streptozotocin-induced diabetic rats. Polish Journal of Pharmacology 2003; 55: 345-351.

Teaching

Neuroecology (Neurobiology, Biology)

Brain and behaviour (Neurobiology)

Principles of neurobiology for veterinary students (Veterinary Medicine)

Animal Psychology (Veterinary Medicine)